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Disposable: | Non-Disposable |
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99% Purity Weight Loss Peptides Therapy 5mg 10mg 15mg vials Tirz CAS 736992-21-5 Lira Sema Lyophilized Powder Fat Burn Slimming Obesity Treatment Retatrutide
Item | value |
Other Names | weight loss slimming Powder |
MOQ | 1 box |
Place of Origin | China |
Usage | weight loss & slimming |
Purity | 99.99% |
Model Number | 736992-21-5 |
Form | lyophilized powder |
Color | white |
Sample | Availiable |
Tirz is revolutionizing the way we manage type 2 diabetes. By harnessing the power of both GLP and GIP receptor agonists, this injectable medication not only helps regulate blood sugar levels effectively but also aids in weight loss - a game-changer for those dealing with both diabetes and obesity. Plus, with just one weekly injection, Tirz offers a simple and convenient treatment option for busy individuals.
The introduction of Tirz represents a pivotal moment in the fight against type 2 diabetes. By melding the benefits of GLP and GIP receptor agonists into a weekly injectable formulation, this medication delivers comprehensive support in controlling blood sugar levels while addressing the challenge of obesity.
Tirz has entered the healthcare arena as a game-changing treatment option for type 2 diabetes. Its unique formulation, which combines G-L-P-1 agonist and GIP receptor agonist actions in a once-weekly injection, promises superior outcomes in glycemic management and weight reduction, offering hope to millions.
In conclusion, Tirz 10mg represents a groundbreaking advancement in the management of T2DM, offering a novel therapeutic approach that combines the benefits of G-L-P-1 and GIP receptor agonism. This peptide-based medication has demonstrated efficacy, safety, and potential cardiovascular benefits in clinical trials, positioning it as a promising option for patients with uncontrolled diabetes. Continued research and real-world experience will further elucidate the role of Tirz in optimizing outcomes and improving the lives of individuals living with T2DM.
The addition of GIP which anatagonizes the central effects of G-L-P-1 to cause nausea is designed to improve tolerability and also allow for more aggressive dosing with increased systemic exposure. A recent post-hoc analysis showed significantly decreased NASH-related biomarkers and increased adiponectin in patients with T2DM
The weight-reducing actions of the GIPR-G-L-P1R co-agonist Tirz.Considerable interest is focused on the mechanisms of action of Tirz, a highly effective GIPR-G-L-P1R co-agonist that produces superior reductions in HbA1c and body weight, relative to that achieved with 1 mg once weekly of Sema in people with T2D. The GIPR is expressed in multiple regions of the mouse and human brain, in subsets of neurons and glial cells, with some hypothalamic and hindbrain cells exhibiting co-expression of the GIPR and G-L-P1R. Chemogenetic activation of GIPR + cells in the mouse hypothalamus acutely reduced food intake; however, co-administration of exendin-4 did not produce an additive reduction of food intake when compared to either intervention alone.
Therapy with Tirz, 5-15 mg once weekly produces 8-12% body weight reduction in people with T2D, prompting ongoing development of Tirz as a weight loss agent for people with overweight or obesity. The importance of GIP for the weight loss properties of tirzepatide in humans is uncertain; however, Tirz failed to reduce body weight in Glp1r−/- mice, implicating a dominant role for the G-L-P1R in the weight loss observed with this agent. Glucose-dependent insulinotropic polypeptide (GIP) has been shown to reduce the extent of aversive responses induced by G-L-P-1 in mice and rats and decrease nausea and vomiting in the shrew.
Specification
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ITEMS
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STANDARDS
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RESULTS
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Appearance
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White to off-white crystalline powder
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Complies
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Appearance of solution(5%w/v in water)
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Colorless to pale yellow and clear
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Complies
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Assay(HPLC)
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≥98%
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98.40%
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Odor & taste
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Unique
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Complies
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Loss on drying
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≤6.0%
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0.4%
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≤1ppm
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<1ppm
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Heavy Metals
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≤20ppm
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<20ppm
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Total plate count
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≤1000cfu/g
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<1000cfu/g
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Yeast and Moulds
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≤100cfu/g
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<100cfu/g
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E.Coli
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Negative
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Negative
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Salmonella
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Negative
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Negative
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Application
Storage:
Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.
Freeze dried powder can be transported for short distances at room temperature. Once you receive the goods, please immediately store them in the refrigeration room. After mixing with sterile water, it should be used within one week.
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Payment & Workshop