| Customization: | Available |
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| Application: | Home |
| Disposable: | Non-Disposable |
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| Product name | L-Carnosine |
| CAS No. | 305-84-0 |
| MF | C9H14N4O3 |
| MW | 226.23 |
| Melting point | 253 °C (dec.) (lit.) |
| Boiling point | 367.84°C (rough estimate) |
| Density | 1.2673 (rough estimate) |
| Storage | DMSO (Very Slightly), Water (Slightly) |
Product Introduction
L-carnosine is a dipeptide the body produces naturally from combining the amino acids alanine and histidine (x). It acts primarily as an antioxidant, and its largest concentration exists in the heart, muscles and brain. Its supplement form fights free-radical damage in cells, advanced glycation end products (harmful compounds the body makes when fat and protein combine with sugar in the blood) and the formation of abnormal proteins in the body.
Over the years, clinical research has had a keen eye on carnosine's antioxidant effects. In fact, one such study, published in Rejuvenation Research, asserts that these effects are responsible for brain stimulation, muscle microcirculation and cellular rejuvenation. The same study states that carnosine's antioxidant effects help prevent "neurodegeneration and the accumulation of senile features." The study concludes with a statement supporting carnosine's ability to assist patients under oxidative stress with high efficacy and no side effects.
Medical researchers have sufficiently documented carnosine's neuroprotective properties in the fight against cerebral ischemia (blood-supply deficiency in the brain). Without an adequate supply of blood, the brain loses oxygen, and when the brain loses oxygen, brain tissue starts to die and the risk of stroke increases. One study, published in the journal Stroke, found that carnosine decreased neuron damage and reactive oxygen species in the brains of mice with cerebral ischemia. At the same time, the study found that it also preserved levels of glutathione (GHS) - a potent antioxidant - in the brain.
Other studies suggest that carnosine helps your nerves function efficiently by managing synapse impulse transmissions. Some have suggested it also helps treat and prevent neurological disorders such as Parkinson's disease and Alzheimer's disease.
An article published in the Journal of Alzheimer's Disease states that carnosine can clear up many of the damaging compounds that contribute to brain degeneration and Alzheimer's, such as:
Carnosine suppresses amyloid-beta peptide toxicity in the Alzheimer's brain by stealing zinc ions from amyloid peptide aggregates. These aggregates form degenerating "senile plaques" in the Alzheimer's brain.
A study published in the journal Amino Acids found that carnosine may have hypoglycemic, hypotensive and lipolytic effects. That is, it may help the body lower blood sugar and blood pressure as well as break down fat. Moreover, this study found that carnosine can help you control your appetite. Researchers suspected it did all this by affecting the nerves in the adrenal glands, stomach, pancreas, kidneys, liver and adipose tissues.
Another study, published in Neuroscience Letters, found that a carnosine solution in drinking water slowed tumor growth in mice that researchers had transplanted human colon cancer cells into. These researchers found that carnosine suppressed splenic sympathetic nerve activity, which boosted the "natural killer" activity of splenic cells, likely responsible for inhibiting tumor growth.
A study published in the journal Amino Acids found that carnosine helped heal wounds in diabetic mice. Patients with diabetes experience complications in wound healing because their disease regulates cellular events that take place during the healing process. During their wound analysis after treating diabetic mice with carnosine, researchers found that the dipeptide "increased expression of growth factors and cytokines genes involved in wound healing." In other words, applying carnosine to wounds in diabetic mice accelerated their healing.
In another study, published in the journal Gut, researchers found that a supplement of zinc and carnosine, zinc carnosine, suppressed gastric and small-intestinal injury in mice by stimulating gut mucosal integrity.
| Items | Specifications | Results |
| Appearance | White to off white powder | White powder |
| Assay (by HPLC) | NLT 97% | 97.64% |
| Purity | NLT 97% | 98.15% |
| Solvent Residue | ≤0.7% | 0.56% |
| NMR (H-NRM) | Conforms | Conforms |
| Conclusion: The Product Conforms to Enterprise Standard |
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Storage:
Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.
Freeze dried powder can be transported for short distances at room temperature. Once you receive the goods, please immediately store them in the refrigeration room. After mixing with sterile water, it should be used within one week.
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