| Customization: | Available |
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| CAS No.: | 111-62-6 |
| Formula: | C20h38o2 |
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| Name: | Ethyl Oleate |
| Melting point | −32 °C(lit.) |
| Boiling point | 216-218 °C15 mm Hg |
| density | 0.87 g/mL at 25 °C(lit.) |
| FEMA | 2450 | ETHYL OLEATE |
| refractive index | n20/D 1.451(lit.) |
| Fp | >230 °F |
| storage temp | -20°C |
| solubility | soluble10% |
| form | Oily Liquid |
| color | Clear |
Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication.
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer.
Ethyl oleate is regulated as a food additive by the Food and Drug Administration under "Food Additives Permitted for Direct Addition to Food for Human Consumption", 21CFR172.515.
Ethyl oleate has been identified as a primer pheromone in honeybees.
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. There is a growing body of research literature that implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, and brain). Among the speculations is that ethyl oleate may be the toxic mediator of alcohol in fetal alcohol syndrome. The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion. Ethyl oleate is not currently approved by the U.S. Food and Drug Administration for any injectable use. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed.
Pharmaceutical Industry
Ethyl oleate is utilized as an ingredient for the preparations of pharmaceutical drugs that involves lipophilic substances such as steroids. Due to its quick degradation of the digestive system, ethyl oleate is employed as a way for intramuscular drug delivery by compounding pharmacies. In some cases, the compound is used in the preparation of day-to-day doses of progesterone in the sustenance of pregnancy.
Food Industry
Ethyl oleate is used as a food additive and is regulated by the Food and Drug Administration. It is also used as a flavouring agent in food.
Application:
*Used as a solvent, a transdermal absorption enhancer, a lubricant and a plasticizer in formulations.
*A suitable solvent for steroids and other lipophilic drugs. Its properties are similar to almond oil and peanut oil, and its viscosity is low, and it is easily absorbed by body tissues.
*Used as biodegradable microcapsules and microemulsions of cyclosporine implanted under the dermis.
* As the solvent of flavor oil, the carrier of essence fragrance in field of food additives.
Storage:
Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.
Freeze dried powder can be transported for short distances at room temperature. Once you receive the goods, please immediately store them in the refrigeration room. After mixing with sterile water, it should be used within one week.
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