Weight Loss Peptide Powder Myostatin CAS 901758-09-6 Gdf-8 for Muscle Building

• Customization: Available
• CAS No.: 901758-09-6
• Formula: C35h48n10o15
• Model NO.: 901758-09-6
• Variety: Dye
• Feature: Stocked
• Usage: Organic Chemical Material
• Status: Solid State
• Purity: 99%
• Sensitive: Air Sensitive
• out Packing Size: 200*400
• Documents: COA
• Assay: HPLC 99%
• Transport Package: Box
• Specification: 10vials/box
• Trademark: Bosetech
• Origin: China
• HS Code: 29225000
• Production Capacity: 50000box/Year

Product Description

Product Description

US Warehouse 2mg/5mg/10mg Weight loss Peptide Powder Myostatin CAS 901758-09-6 Gdf-8 for Muscle Building

Product Name	Top quality GDF-8
Packing	1box/10vials,1mg/vial
CAS No	901758-09-6
Molecular Formula	C221H366N72O67S
Application	Pharmaceutical raw materials
purity	> 99.0%

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.
Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

Function & Application

The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".

Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

 

Items	Specifications	Results
Appearance	White to off white powder	White powder
Assay (by HPLC)	NLT 97%	97.64%
Purity	NLT 97%	98.15%
Solvent Residue	≤0.7%	0.56%
NMR (H-NRM)	Conforms	Conforms
Conclusion: The Product Conforms to Enterprise Standard

Secondary endpoints:

The average change in body weight from baseline to 32 weeks was higher in the CagriSema group than in the canaglitide group (P<0.0001) and the sema group (P<0.0001).


The average changes in body weight of the 3 groups are:

CagriSema group: -15.6%;

Sema group: -5.1%;

Canaglitide group: -8.1%.
The average change in fasting blood glucose from baseline to 32 weeks was higher in the CagriSema group than in the canaglitide group (P=0.0010), but there was no significant difference compared with the sema group (P=0.10).

The average changes in fasting blood glucose in the 3 groups are:

CagriSema group: -3.3 mmol/L;

Sema group: -2.5 mmol/L;

Canaglitide group: -1.7 mmol/L.

At baseline, the CagriSema group, sema group and canaglitide group spent 45.9%, 32.6% and 56.9% of their time within the range of 3.9~10.0 mmol/L respectively, and at week 32 they were 88.9% and 76.2 respectively. % and 71.7%.

 
Adverse events were reported by 21 (68%) subjects in the CagriSema group, 22 (71%) subjects in the sema group, and 24 (80%) subjects in the canaglitide group. The most common adverse events were mild or moderate gastrointestinal disorders. In addition, no grade 2 or 3 hypoglycemic events or fatal adverse events were reported in this study.

Overall, treatment with CagriSema resulted in clinically relevant improvements in glycemic control. The average change in HbA1c in the CagriSema group was greater than that in the canaglitide group, but there was no significant difference compared with the sema group. In addition, patients in the CagriSema group experienced significantly greater weight loss compared with the sema and canaglitide groups and were well tolerated. These data support a longer, larger Phase 3 study of CagriSema in this population.
 

Clients FeedBack

 

Packaging & Shipping

 
Product Packing

1. Usually in bare bottle packaging;

2. 5mg/10mg/15mg per vial, 10 vials/box;

3. The outer packaging is usually a white cardboard box without any labels;

4. We can provide simple text label customization services, without providing colored labels;

5. Generally, a maximum of 25 boxes can be sent per package.

Storage:

Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.

Freeze dried powder can be transported for short distances at room temperature. Once you receive the goods, please immediately store them in the refrigeration room. After mixing with sterile water, it should be used within one week.
 

Packing & Delivery

 

 

 

 

To better ensure the safety of your goods, professional, environmentally friendly, convenient and efficient packaging services will be provided.
We will deliver the goods intact to you by express.
If you want to know the shipping cost, please send an inquiry with your address.
 

Payment & Workshop

 

Company Profile

Hubei Bosi Huike Trading Co., Ltd. is located in Wuhan Donghu High-Tech Economic Development Zone, specilize in production and exportation of pharmaceutical raw materials and intermediates, peptides, cosmetic ingredients, has invested and closed cooperated with domestic manufacturers and Laboratories from famous Universities to meet the different customers' needs from grams to tonnage quantity.

We always stand in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers.

We have business with more than 60 countries, of which our main markets include Central and South America, Southeast Asia, Central Asia, Africa, Middle East, Eastern Europe, Russia and more and more higher regulative markets are being developed as long as our deep ploughing.

 

What services can we provide?

Accepted Delivery Terms: FOB, CIF, EXW, Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,HKD,CNY;
Accepted Payment Type: T/T,MoneyGram,PayPal,Western Union,BTC;
Language Spoken: English, Chinese, Spanish, French, German, Portuguese, Russian.

1. We supply Peptides, APIs & Intermediates, Anti-hairloss, Oil, Food Additive and so on to satisfy your needs;
2. We will reply you for your inquiry in 24 hours;
3. Our Q&C team will inspect every product quality strictly before delivery;
4. After delivery, we will track the products for you once every two days, until you get the products. When you got the goods, if you have any questions about the problem, contact with us, we will offer the solve way for you

 

FAQ

Q1: What's your MOQ?
A:MOQ is 1KG.

Q2: How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?
A:Different quantity has different discount.

Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6. We don't know you at all, how can we trust you?

A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.

Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.