Customization: | Available |
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CAS No.: | 38304-91-5 |
Formula: | C9h15n5o |
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99% Purity Janoshik Lab Safe Shipping Bosi Huike Factory Supply API 99% Minoxidil Raw Material Anti-Hair Loss CAS 38304-91-5 Minoxidil
Product Name | Minoxldil |
Appearance | White Powder |
CAS | 38304-91-5 |
MF | C9h15n5o |
MW | 209.251 G/Mol |
Storage | Cool Dry Place |
Shelf Life | 24 months |
Introduction |
Minoxidil, whose chemical name is 6-(1-piperidinyl)-2,4-pyrimidinediamine-3-oxide, is an organic substance that is white or off-white crystalline powder. Clinically, as a potassium channel opener, it can directly relax vascular smooth muscle, and has a powerful small arterial expansion effect, which reduces peripheral resistance and blood pressure without affecting the volume of blood vessels, so it can promote venous return. At the same time, due to reflex regulation and positive frequency effects, cardiac output and heart rate can be increased, but it does not cause orthostatic hypotension. |
Function |
(A)Minoxidil Powder can stimulate the proliferation and differentiation of hair follicle epithelial cells: the normal human hair follicle epithelial cells in different concentrations of minoxidil solution in the micro-molar concentration of minoxidil can stimulate hair follicle epithelial cell proliferation. (B)Minoxidil Powder can promote angiogenesis: increase the local blood supply: hair growth depends on the hair nipple blood supply network nutrition, hair in the different growth cycle, vascular endothelial growth mRNA expression is different from the growth of vascular endothelial growth mRNA in the dermis Nipple cells were strongly expressed, but were less expressed during retrograde and resting periods. (C)Minoxidil Powde can open potassium channels: potassium channel opening is an important step in regulating hair growth, animal models in vitro and in vivo experiments have shown that minoxidil is a potassium channel activator, can increase the permeability of potassium ions to prevent calcium ion flow Intracellular, resulting in decreased free calcium concentration in cells, while calcium ions, epidermal growth inhibit hair growth. |
Application |
Minoxidil can be used for refractory hypertension and renal hypertension, the antihypertensive effects of hydralazine stronger than that. Mechanism for the K + channel opening, so that vascular smooth muscle. it Is a vasodilator antihypertensive drug classes. Does not cause orthostatic hypotension, no long-term efficacy of medication. Minoxidil was the first drug approved b for the treatment of androgenetic alopecia (hair loss).Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure that included hair growth and reversal of male baldness. We offer a wide range of minoxidil solutions: The content is female (2%, 3%), unisex (5%), and men (15%); |
Storage:
Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.
Freeze dried powder can be transported for short distances at room temperature. Once you receive the goods, please immediately store them in the refrigeration room. After mixing with sterile water, it should be used within one week.
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